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Search Results for " prostate cancer "

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カタログ番号	製品名	別名	ターゲット
T22263	Bavdegalutamide	ARV-110	Androgen Receptor
	Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati...		Androgen Receptor
T0380	Bicalutamide	ICI-176334	Androgen Receptor , Autophagy
	Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.		Androgen Receptor , Autophagy
T8858	DTHIB		HSP
	DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.		HSP
T7690	2-hydroxy Flutamide		Androgen Receptor
	2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer		Androgen Receptor
T60051	VPC-18005		Others
	VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.		Others
T3160	HUHS015		Others
	HUHS015 is a potent PCA-1/ALKBH3 inhibitor.		Others
T8217	Enzalutamide carboxylic acid		Androgen Receptor , Drug Metabolite
	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .		Androgen Receptor , Drug Metabolite
T9721	ML339		CXCR
	ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.		CXCR
T16522	Phenoxodiol	Dehydroequol,Idronoxil,Haginin E	Apoptosis , IAP , Caspase , Topoisomerase , p53
	Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apop...		Apoptosis , IAP , Caspase , Topoisomerase , p53
T39695	ARD-2128		Androgen Receptor
	ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protein levels, suppressing AR-regulated gene expression in tumor...		Androgen Receptor
T12928	SK33		Androgen Receptor
	SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.		Androgen Receptor
T25492	Hepln-13	Hepln 13,Hepln13	c-Met/HGFR
	Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.		c-Met/HGFR
T9266	Fatostatin		Lipid , Fatty Acid Synthase
	Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.		Lipid , Fatty Acid Synthase
T6889	MI-136		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
	MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
T13273	UT-34		Androgen Receptor
	UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prost...		Androgen Receptor
T6400	AZD3514		Androgen Receptor
	AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.		Androgen Receptor
T1855	ZCL278	ZCL 278	CDK , Ras
	ZCL278 is a selective Cdc42 GTPase inhibitor.		CDK , Ras
T38684	AKR1C3-IN-4	AKR1C3-IN-4	NADPH
	AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.		NADPH
T0272	Nilutamide	RU23908	Androgen Receptor
	Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...		Androgen Receptor
T9246	JNJ-63576253		Androgen Receptor
	JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).		Androgen Receptor
T10717	Inobrodib	CBP-IN-1	Epigenetic Reader Domain
	Inobrodib (CBP-IN-1) is a potent inhibitor of p300/CBP bromodomain.		Epigenetic Reader Domain
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T6308	Stattic	STAT3 Inhibitor V	Apoptosis , STAT
	Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis.		Apoptosis , STAT
T6916	OICR-9429	OICR 9429	Histone Methyltransferase , JAK
	OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.		Histone Methyltransferase , JAK
T36841	IPI-9119		Fatty Acid Synthase
	IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).		Fatty Acid Synthase
T27730	KGP94	KGP-94,KGP 94	Cysteine Protease
	KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).		Cysteine Protease
T1267	Abacavir	Epzicom,Ziagen,Abacavir sulfate	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.		Apoptosis , HIV Protease , Reverse Transcriptase
T9179	CLP-3094	2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GP...		Androgen Receptor
T3630	Relugolix	RVT-601,TAK-385	GNRH Receptor
	Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...		GNRH Receptor
T1167	Cyproterone acetate	Androcur,Cyproterone 17-O-acetate	Androgen Receptor
	Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. ...		Androgen Receptor
T6367	Abacavir sulfate	Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity		Apoptosis , HIV Protease , Reverse Transcriptase
T8933	JNJ-63576253 free base	TRC253,JNJ-63576253	Androgen Receptor
	JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the re...		Androgen Receptor
T9245	TRPM4-IN-1	CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.		TRP/TRPV Channel
T6832	Fatostatin hydrobromide	Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1 , Fatty Acid Synthase
	Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.		NPC1L1 , Fatty Acid Synthase
T4451	Estramustine phosphate sodium	Ro 21-8837/001,Estramustine phosphate disodium	Apoptosis , Microtubule Associated
	Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.		Apoptosis , Microtubule Associated
T4102	Goserelin acetate	Fertilan,ICI-118630 acetate,Zoladex	Apoptosis , GNRH Receptor
	Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.		Apoptosis , GNRH Receptor
T14511	BAY1082439		Apoptosis , PI3K
	BAY1082439, an orally bioavailable, selective inhibitor of PI3Kα/β/δ, demonstrates high efficacy in inhibiting the growth of Pten-null prostate cancer [1][2]. Additionally, BAY1082439 is effective against mutated forms o...		Apoptosis , PI3K
T0860L	Mefloquine	Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998	Others
	Mefloquine (Ro 215998), a quinoline antimalarial agent, is an anti-SARS-CoV-2 entry inhibitor. Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic l...		Others
T0487	Metoprolol tartrate	CGP 2175E	Adrenergic Receptor
	Metoprolol Tartrate is a blocker of the cardioselective β-adrenergic receptor.		Adrenergic Receptor
T21308	Histrelin	Supprelin LA,Histrelin Acetate	Others
	Histrelin (Supprelin LA) acetate is a nonapeptide analog of gonadotropin-releasing hormone (GnRH) with added potency. It is considered a GnRH agonist. Histrelin is used in the treatment of hormone-sensitive cancers of th...		Others
T28238	ONC1-13B	ONC-1-13B,ONC 1 13B,ONC-113B,ONC 113B
	ONC1-13B, an androgen receptor antagonist, is used potentially for the treatment of prostate cancer.
T16901	SMIP004		Apoptosis , Others , E1/E2/E3 Enzyme
	SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.		Apoptosis , Others , E1/E2/E3 Enzyme
T28189	Nortopixantrone HCl	BBR3438,Nortopixantrone hydrochloride,BBR-3438	Others
	Nortopixantrone HCl (BBR 3438) is a novel 9-azacyclonopyrazole that shows antitumor activity in a human prostate cancer model.		Others
T8925	Glu-urea-Lys
	Glu-urea-Lys is a molecular scaffold that targets PSMA and can be used as a prostate cancer imaging agent to study prostate-specific membrane antigens.
T13312L	Seviteronel	VT-464	P450 , Androgen Receptor
	Seviteronel (VT-464) is a novel CYP17 cleavage enzyme inhibitor and androgen receptor antagonist for the study of breast and prostate cancer.		P450 , Androgen Receptor
T15205	EL-102	EL102	Microtubule Associated , HIF
	EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.		Microtubule Associated , HIF
T23647	Zindoxifene	D 16726	Estrogen/progestogen Receptor
	Zindoxifene (D 16726) is an anti-estrogenic compound with antitumor activity that can be used in studies of breast and prostate cancer.		Estrogen/progestogen Receptor
T71534L	CIA-1 (Free base)	CIA-1(Free base）	Gamma-secretase
	CIA-1 (Free base) is a nuclear receptor COUP-TFII inhibitor with IC50 values ranging from 1.2 μM to 7.6 μM in prostate cancer cell lines. CIA-1 (Free base) inhibits tumor growth in a mouse model of prostate cancer xenogr...		Gamma-secretase
T0040	Quinestrol	W-3566,Ethinylestradiol 3-cyclopentyl ether,EE2CPE	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Quinestrol (Ethinylestradiol 3-cyclopentyl ether) is a synthetic estrogen, applied in hormone replacement therapy, and occasionally to use in cancer and prostate cancer treatment.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T67818	BMS-641988		Androgen Receptor
	BMS-641988 is a novel nonsteroidal androgen receptor antagonist for the treatment of prostate cancer.		Androgen Receptor

Compounds

Bavdegalutamide

T22263

Synonym: ARV-110

Target: Androgen Receptor

Bicalutamide

T0380

Synonym: ICI-176334

Target: Androgen Receptor, Autophagy

Target: Androgen Receptor

Enzalutamide carboxylic acid

T8217

Synonym:

Target: Androgen Receptor, Drug Metabolite

Synonym: Dehydroequol,Idronoxil,Haginin E

Target: Apoptosis, IAP, Caspase, Topoisomerase, p53

ARD-2128

T39695

Synonym:

Target: Androgen Receptor

SK33

T12928

Synonym:

Target: Androgen Receptor

Hepln-13

T25492

Synonym: Hepln 13,Hepln13

Target: Lipid, Fatty Acid Synthase

MI-136

T6889

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, Androgen Receptor

UT-34

T13273

Synonym:

Target: Androgen Receptor

AZD3514

T6400

Synonym:

Target: Androgen Receptor

Target: Androgen Receptor

JNJ-63576253

T9246

Synonym:

Target: Androgen Receptor

Inobrodib

T10717

Synonym: CBP-IN-1

Target: Epigenetic Reader Domain

PHPS1

T28410

Synonym: PHPS-1,PHPS 1

Target: Phosphatase

Stattic

T6308

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

OICR-9429

T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

IPI-9119

T36841

Synonym:

Target: Fatty Acid Synthase

KGP94

T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

Abacavir

T1267

Synonym: Epzicom,Ziagen,Abacavir sulfate

Target: Apoptosis, HIV Protease, Reverse Transcriptase

CLP-3094

T9179

Synonym: 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

Target: Androgen Receptor

Relugolix

T3630

Synonym: RVT-601,TAK-385

Target: GNRH Receptor

Cyproterone acetate

T1167

Synonym: Androcur,Cyproterone 17-O-acetate

Target: Androgen Receptor

Abacavir sulfate

T6367

Synonym: Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

JNJ-63576253 free base

T8933

Synonym: TRC253,JNJ-63576253

Target: Androgen Receptor

TRPM4-IN-1

T9245

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

Fatostatin hydrobromide

T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

Estramustine phosphate sodium

T4451

Synonym: Ro 21-8837/001,Estramustine phosphate disodium

Target: Apoptosis, Microtubule Associated

Goserelin acetate

T4102

Synonym: Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

BAY1082439

T14511

Synonym:

Target: Apoptosis, PI3K

Mefloquine

T0860L

Synonym: Ro215998,WR 142490,Ro-215998,Lariam,Ro 215998

Target: Adrenergic Receptor

Histrelin

T21308

Synonym: Supprelin LA,Histrelin Acetate

Target: Others

ONC1-13B

T28238

Synonym: ONC-1-13B,ONC 1 13B,ONC-113B,ONC 113B

Target: Apoptosis, Others, E1/E2/E3 Enzyme

Nortopixantrone HCl

T28189

Synonym: BBR3438,Nortopixantrone hydrochloride,BBR-3438

Target: P450, Androgen Receptor

EL-102

T15205

Synonym: EL102

Target: Microtubule Associated, HIF

Zindoxifene

T23647

Synonym: D 16726

Target: Estrogen/progestogen Receptor

CIA-1 (Free base)

T71534L

Synonym: CIA-1(Free base）

Target: Gamma-secretase

Quinestrol

T0040

Synonym: W-3566,Ethinylestradiol 3-cyclopentyl ether,EE2CPE

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

BMS-641988

T67818

Synonym:

Target: Androgen Receptor

カタログ番号	製品名	別名	ターゲット
TN7020	Astragenol		Others
	Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research.		Others
T8188	Podophyllotoxone		Others , Microtubule Associated
	Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.		Others , Microtubule Associated
TN2097	Pomolic acid		Apoptosis , Caspase , HIV Protease , AMPK
	Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.		Apoptosis , Caspase , HIV Protease , AMPK
T1134	Clofoctol		Antibacterial , Antibiotic
	Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections.		Antibacterial , Antibiotic
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T3878	Raddeanin A	NSC382873,Anemodeanin A,Raddeanin R3	Apoptosis , HDAC
	Raddeanin A (NSC-382873) has moderate inhibitory activity against histone deacetylases (HDACs). Raddeanin A has high antiangiogenic potency, antitumor activity.		Apoptosis , HDAC
T6485	Embelin	NSC 91874,Emberine,Embelic acid	Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
	Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
T34394	Rotenolone	Rotenolone I,12alpha-HYDROXYROTENONE	Others
	Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus.		Others
T6290	Tanespimycin	17-AAG,CP 127374,NSC 330507,KOS 953	Apoptosis , Mitophagy , HSP , Antibacterial , Antibiotic , Autophagy
	Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
T2S1797	Santalol		Antioxidant , Antifungal
	1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal ef...		Antioxidant , Antifungal
T2895	Lupeol	Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis , Androgen Receptor , Akt
	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.		Apoptosis , Androgen Receptor , Akt
T4869	D-Allose	β-D-Allopyranose,D-(+)-ALLOSE	Others , Endogenous Metabolite
	D-Allose (β-D-Allopyranose) is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refractory prostate cancer ...		Others , Endogenous Metabolite
T6S1255	Ophiopogonin-D		ROS
	Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1, OPD may be developed as a potential anti-prostate cancer agent.		ROS
TMS0418	Dihydroergotoxine mesylate	Ergoloid mesylates	GABA Receptor
	Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.		GABA Receptor
TQ0214	Dimethylcurcumin	ASC-J9,GO-Y025	Androgen Receptor
	Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.		Androgen Receptor
T7873	Iberverin		Others
	Iberverin is a naturan product. It induces phase II enzyme activity and decreases expression of androgen receptors in prostate cancer cells.		Others
T14008	2,2,5,7,8-Pentamethyl-6-Chromanol	PMC	Androgen Receptor
	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.		Androgen Receptor
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
T13518	5α-Pregnane-3β,6α-diol-20-one		Others
	5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation.		Others
T2543	Cabazitaxel	XRP6258,RPR-116258A,TXD 258,taxoid XRP6258	Microtubule Associated , Autophagy
	Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.		Microtubule Associated , Autophagy
TN1805	Isosilybin B		Apoptosis , Androgen Receptor
	Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr...		Apoptosis , Androgen Receptor
T4767	Formamide	Carbamaldehyde,Methanamide,NSC 748,Formimidic acid	Others , Endogenous Metabolite
	Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent deve...		Others , Endogenous Metabolite
T17280	(Z)-Guggulsterone		Apoptosis , VEGFR , Akt
	(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.		Apoptosis , VEGFR , Akt
T25192	Butyrolactone I	Olomoucin	CDK
	Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.		CDK
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
T3851	Vicenin 2	Vicenin -2	RAAS
	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,...		RAAS
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
TN1013	Cucurbitacin D		Apoptosis
	Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production in metastatic PrC, and induces inflammasome activation ind...		Apoptosis
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
T4000	(±)-Equol	Equol,(R,S)-Equol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite
	(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu...
T6S0735	Flavokawain B	Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone	Apoptosis , Others
	1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...		Apoptosis , Others
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
TN3416	Angelol M		Others
	Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.		Others
TN5878	7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin
	7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.
T3245L	Carvone	AI3 27596,BRN 1861032,L-Carveol,BRN-1861032,BRN1861032
	Carvone is an agonist of TRPV3 found in spearmint oil. It suppresses cell proliferation in prostate cancer cells and inhibits the growth of Dermatophagoides.
TN6638	(E)-6-O-(p-coumaroyl)scandoside methyl ester
	(E)-6-O-(p-coumaroyl)scandoside methyl ester shows moderate anti-proliferation effect on PC3 human androgen-independent prostate cancer cells.
TN6337	Lupichromone	5,7-Dihydroxy-6,8-diprenylchromone
	Eriosemation significant androgen receptor (AR) inhibition activity, suggests that it could be a promising candidate for further evaluation for prostate cancer prevention or management.
TN4352	Jatamanvaltrate B		Others
	Jatamanvaltrate B shows cytotoxicity against lung adenocarcinoma (A549), metastatic prostate cancer (PC-3M), colon cancer (HCT-8),and hepatoma (Bel7402) cell lines.		Others
TN6059	Demethoxyfumitremorgin C
	Demethoxyfumitremorgin C and tryprostatin B are fungal inhibitors of mammalian cell cycle progression at the G(2)/M transition. Demethoxyfumitremorgin C inhibits the proliferation of PC3 human prostate cancer cells via t...
TN3737	Cycloartane-3,24,25-triol		ATPase
	Cycloartane-3,24,25-triol has potential for development as an anti-cancer agent against prostate cancer. It reduces the viability of PC-3 and DU145 cell lines with IC50 values of 2.226 ± 0.28 μM and 1.67 ± 0.18 μM respec...		ATPase
TN4963	Scillascillin		Others
	Scillascillin has anticancer activity, it is significantly active against human cancer cell lines MCF-7 (breast cancer) and DU-145 (prostate cancer) with inhibitory concentration (IC)50 values 9.59 and 11.32 ug/ml respec...		Others
T72802	Spongionellol A
	Spongionellol A, an inhibitor of MDR1 (p-glycoprotein), exhibits significant cytotoxicity and selectivity towards prostate cancer cells through the induction of caspase-dependent apoptosis. This compound is valuable for ...
TN1872	Linderone		Others
	Linderone A shows anticancer activity against A549 non-small cell lung cancer cells and PC-3 prostate adenocarcinoma cell line.		Others
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天然物製品

Target: Others, Microtubule Associated

Pomolic acid

TN2097

Synonym:

Target: Apoptosis, Caspase, HIV Protease, AMPK

Clofoctol

T1134

Synonym:

Target: Antibacterial, Antibiotic

Agrimol B

T4S1173

Synonym:

Target: Sirtuin, PPAR

Wedelolactone

T3384

Synonym: IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Forskolin

T2939

Synonym: Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Lycorine

T3324

Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Raddeanin A

T3878

Synonym: NSC382873,Anemodeanin A,Raddeanin R3

Target: Apoptosis, HDAC

Embelin

T6485

Synonym: NSC 91874,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

4,5-Dicaffeoylquinic acid

T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Rotenolone

T34394

Synonym: Rotenolone I,12alpha-HYDROXYROTENONE

Target: Others

Tanespimycin

T6290

Synonym: 17-AAG,CP 127374,NSC 330507,KOS 953

Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy

Santalol

T2S1797

Synonym:

Target: Antioxidant, Antifungal

Lupeol

T2895

Synonym: Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol

Target: Apoptosis, Androgen Receptor, Akt

D-Allose

T4869

Synonym: β-D-Allopyranose,D-(+)-ALLOSE

Target: Others, Endogenous Metabolite

Dihydroergotoxine mesylate

TMS0418

Synonym: Ergoloid mesylates

Target: GABA Receptor

Dimethylcurcumin

TQ0214

Synonym: ASC-J9,GO-Y025

Target: Androgen Receptor

2,2,5,7,8-Pentamethyl-6-Chromanol

T14008

Synonym: PMC

Target: Androgen Receptor

9-hydroxy-4-androstene-3,17-dione

T7990

Synonym:

Target: Others

5α-Pregnane-3β,6α-diol-20-one

Synonym: XRP6258,RPR-116258A,TXD 258,taxoid XRP6258

Target: Microtubule Associated, Autophagy

Isosilybin B

TN1805

Synonym:

Target: Apoptosis, Androgen Receptor

Formamide

T4767

Synonym: Carbamaldehyde,Methanamide,NSC 748,Formimidic acid

Target: Others, Endogenous Metabolite

(Z)-Guggulsterone

T17280

Synonym:

Target: Apoptosis, VEGFR, Akt

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Target: Apoptosis, Tyrosinase, PPAR, ABC

Silibinin

T1660

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

(±)-Equol

T4000

Synonym: Equol,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Flavokawain B

T6S0735

Synonym: Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Target: Apoptosis, Others

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin

Synonym: AI3 27596,BRN 1861032,L-Carveol,BRN-1861032,BRN1861032

Target:

(E)-6-O-(p-coumaroyl)scandoside methyl ester

Synonym: 5,7-Dihydroxy-6,8-diprenylchromone

Demethoxyfumitremorgin C

TN6059

Synonym:

Target:

Cycloartane-3,24,25-triol

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA...
TMPJ-00514	ACPP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastas...
TMPY-04764	PCK2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol...
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPK-01387	EPhA3 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude...
TMPK-01375	PRLR Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPK-00547	PRLR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ...
TMPY-04205	AGR3 Protein, Human, Recombinant (mFc)	Human	HEK293 Cells
	Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associat...
TMPJ-00733	SPINK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise...
TMPY-06226	SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Along with the SLC30 family, SLC39 family members regulate zinc movement in cells. SLC39 metal ion transporters accumulate zinc into the cytosol. SLC39A6, also known as LIV-1, belongs to a new subfamily of Zrt, Irt-like ...
TMPK-00073	TDGF1/Cripto Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TDGF1 (CRIPTO) is a member of the epidermal growth factor-Cripto-1/FRL-1/Cryptic (EGF/CFC) gene family and an obligate co-receptor involved in NODAL signaling, a developmental program implicated in midline, forebrain, an...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPJ-00157	CD82 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemoki...
TMPY-04025	CEP57 Protein, Human, Recombinant (GST)	Human	E. coli
	CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between...
TMPU-00004	STAT5A Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate canc...
TMPJ-00852	CCL2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Monocyte chemoattractant protein 1 (MCP-1), also called CCL2, is a member of the beta (C-C) subfamily of chemokines that is a chemoattractant for monocytes and basophils but not eosinophils or neutrophils. CCL2 binds the...
TMPJ-01309	PKI-Beta Protein, Human, Recombinant (His)	Human	E. coli
	cAMP-Dependent Protein Kinase Inhibitor β (PKI-β) is a member of the PKI family. As a member of the cAMP-dependent protein kinase inhibitor family,It has been shown that PKI-β is an extremely potent competitive inhibitor...
TMPJ-00917	S100P Protein, Human, Recombinant (His)	Human	E. coli
	Protein S100-P (S100P) belongs to the S100 family of Calcium-Binding Proteins. S100P is 95 amino acids in length and it contains 2 EF-Hand Calcium-Binding Motifs. The EF-Hand Motif binds calcium, which likely alters mole...
TMPY-02122	IFNGR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disea...
TMPJ-00291	IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated	Human	HEK293 Cells
	Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to...
TMPY-04126	MUSTN1 Protein, Human, Recombinant (His)	Human	E. coli
	MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is ...
TMPY-04040	CLEC2D Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were de...
TMPY-04408	CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in pro...
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc)	Human	HEK293 Cells
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPJ-01089	TFF1 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Trefoil Factor 1 (TFF1) belongs to the three structurally related secreted proteins that contain trefoil domains.TFF1 is an approximately peptide that has an important effect in epithelial regeneration and wound healing...
TMPY-00867	Kallikrein 13/KLK13 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Tissue kallikrein 13 (hK13), also known as KLK-L4 (kallikrein-like gene 4), is a member of the human tissue kallikrein family of serine proteases having diverse physiological functions in many tissues. The KLK13 gene res...
TMPY-04484	ACK1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	ACK1 (also known as ACK, TNK2, or activated Cdc42 kinase) is a structurally unique non-receptor tyrosine kinase that is expressed in diverse cell types. This downstream effector of CDC42 mediates CDC42-dependent cell mig...
TMPY-01416	OLFM4 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Olfactomedin-4, also known as G-CSF-stimulated clone 1 protein, Antiapoptotic protein GW112, and OLFM4, is a secreted protein that contains one olfactomedin-like domain. The OLFM4 gene was recently reported to inhibit va...
TMPJ-00698	BTNL2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Butyrophilin-like 2 (BTNL2) is a member of the BTN/MOG Ig-superfamily and functions as a negative regulator of immune cell activation. Mouse BTNL2 is type I transmembrane glycoprotein that contains an extracellular domai...
TMPJ-01158	ALK-2/ACVR1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Activin RIA, also known as ALK-2, TSK-7L, SKR1, TSR-I, and ACTR-I, is a glycosylated 65 kDa type I receptor in the TGF-beta serine/threonine kinase receptor family. Binding of TGF-beta superfamily ligands induces formati...

Kallikrein 3/KLK3 Protein, Human, Recombinant (His)

TMPY-02258

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Human, Recombinant (hFc)

TMPK-00728

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (hFc)

TMPK-00906

Species: Mouse

Expression System: HEK293 Cells

IL-17Rc Protein, Human, Recombinant (hFc)

TMPK-00703

Species: Human

Expression System: HEK293 Cells

ACPP Protein, Human, Recombinant (His)

TMPJ-00514

Species: Human

Expression System: HEK293 Cells

PCK2 Protein, Human, Recombinant (His & GST)

TMPY-04764

Species: Human

Expression System: Baculovirus Insect Cells

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

EPhA3 Protein, Canine, Recombinant (His)

TMPK-01387

Species: Canine

Expression System: HEK293 Cells

PRLR Protein, Canine, Recombinant (hFc)

TMPK-01375

Species: Canine

Expression System: HEK293 Cells

PRLR Protein, Cynomolgus, Recombinant (His)

TMPK-00547

Species: Cynomolgus

Expression System: HEK293 Cells

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

TMPJ-00891

Species: Human

Expression System: HEK293 Cells

AGR3 Protein, Human, Recombinant (mFc)

TMPY-04205

Species: Human

Expression System: HEK293 Cells

SPINK1 Protein, Human, Recombinant (His)

TMPJ-00733

Species: Human

Expression System: HEK293 Cells

SLC39A6/LIV-1 Protein, Cynomolgus, Recombinant (His)

TMPY-06226

Species: Cynomolgus

Expression System: HEK293 Cells

TDGF1/Cripto Protein, Human, Recombinant (His)

TMPK-00073

Species: Human

Expression System: HEK293 Cells

TNFAIP8 Protein, Human, Recombinant (His)

TMPY-03416

Species: Human

Expression System: E. coli

CD82 Protein, Human, Recombinant (hFc)

TMPJ-00157

Species: Human

Expression System: HEK293 Cells

CEP57 Protein, Human, Recombinant (GST)

TMPY-04025

Species: Human

Expression System: E. coli

STAT5A Protein, Human, Recombinant (His)

TMPU-00004

Species: Human

Expression System: E. coli

CCL2 Protein, Rat, Recombinant (His)

TMPJ-00852

Species: Rat

Expression System: HEK293 Cells

PKI-Beta Protein, Human, Recombinant (His)

TMPJ-01309

Species: Human

Expression System: E. coli

S100P Protein, Human, Recombinant (His)

TMPJ-00917

Species: Human

Expression System: E. coli

IFNGR2 Protein, Mouse, Recombinant (His)

TMPY-02122

Species: Mouse

Expression System: HEK293 Cells

IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated

TMPJ-00291

Species: Human

Expression System: HEK293 Cells

MUSTN1 Protein, Human, Recombinant (His)

TMPY-04126

Species: Human

Expression System: E. coli

CLEC2D Protein, Rat, Recombinant (hFc)

TMPY-04040

Species: Rat

Expression System: HEK293 Cells

CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)

TMPY-04408

Species: Human

Expression System: Baculovirus Insect Cells

TMPRSS2 Protein, Human, Recombinant (His & Myc)

TMPH-02237

Species: Human

Expression System: HEK293 Cells

TMPRSS2 Protein, Human, Recombinant (E. coli, His)

TMPH-02236

Species: Human

Expression System: E. coli

TFF1 Protein, Mouse, Recombinant (His)

TMPJ-01089

Species: Mouse

Expression System: HEK293 Cells

Kallikrein 13/KLK13 Protein, Human, Recombinant (His)

TMPY-00867

Species: Human

Expression System: HEK293 Cells

ACK1 Protein, Human, Recombinant (GST)

TMPY-04484

Species: Human

Expression System: Baculovirus Insect Cells

OLFM4 Protein, Human, Recombinant (His)

TMPY-01416

Species: Human

Expression System: HEK293 Cells

BTNL2 Protein, Mouse, Recombinant (His)

TMPJ-00698

Species: Mouse

Expression System: HEK293 Cells

ALK-2/ACVR1 Protein, Human, Recombinant (hFc)

TMPJ-01158

Species: Human

Expression System: HEK293 Cells

カタログ番号	製品名
L2195	Anti-Prostate Cancer Compound Library	2070 compounds
	2070 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.
L2192	Anti-Pancreatic Cancer Compound Library	2238 compounds
	A unique collection of 2238 pancreatic cancer related compounds can be used in HTS and HCS;
L4300	Wnt/Hedgehog/Notch Compound Library	237 compounds
	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L8710	Cuproptosis Compound Library	400 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.

ライブラリー

Anti-Prostate Cancer Compound Library

L2195

Compounds: 2070

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2238

Wnt/Hedgehog/Notch Compound Library

L4300

Compounds: 237

Cuproptosis Compound Library

L8710

Compounds: 400